The special issue contains a monograph by P. P. Nechypurenko, S. O. Semerikov, L. I. Tomilina, in which the system of senior pupils’ research competencies in the chemistry profile learning is designed, the model of formation of senior pupils’ research competencies in the chemistry profile learning using ICT is theoretically grounded and the methodic of using information and communication technologies as tools of forming the senior pupils’ research competencies in the chemistry profile learning is developed.